Falmouth Cafe Sci
The splice of life
Cellular rejuvenation by restoring the fine tuning of gene expression
with Lorna Harries,
Professor in Molecular Genetics, Exeter Uni.
20th November 2019,
Falmouth Polytechnic, Church St.
Cells adapt to their environment by changing the output from their genes. This is critical for successful ageing, and when it goes wrong, diseases such as cancer, cardiovascular disease and dementia result.
When a gene is activated, it makes a message called an RNA, which tells the cell how to make whatever the gene makes. Each gene is actually able to make more than one thing, which is how the cell is able to effectively respond to its internal and external environment.
The ability of the cell to decide which form to make however decreases with age, which we have found to be one of the drivers of these age-related diseases. In this talk, Lorna will outline how we are able to restore the decision making machinery in old cells of different tissue types and effectively rejuvenate human cells in the laboratory.
We hope this breakthrough in understanding will form the basis for a whole new generation of treatments for the diseases of agei
Please note: the rather ghostly impression of a sad face in the image above is actually in the original microscopy image.
NB: All Cafe Sci events held at the Poly are free - unless for special events - but there is a £1 'voluntary' admission charge for use of the building - a small contribution to the Poly's fund for restoration and development of the building.
Please do take note: after seemingly endless re-configuration, (for details see a potted history: HERE) the Falmouth Cafe Sci programme will be fully incorporated into the Cornwall Science Community in 2020.
For more on the future programme of the new CSC, see the website: https://cornwallsciencecommunity.org/
NB: This website site isn't interactive. This kind of (free) software is good for lengthy content, but not for discussion.
But you can follow developments, and comment on the idea, the programme, or individual talks, via the Falmouth Cafe Sci Facebook page.
(With apologies to all those who hate Facebook. But if you can suggest a better interactive web programme - please do!)
The CSC was originally set up to be a local branch of the British Science Association - the BSA - until the BSA decided to close down its branch structure.
Nevertheless, we do still hold with the BSA's view of science:
"It’s not just a list of facts – it’s a mindset owned by anyone who approaches the world in an open-minded, sceptical, logical, systematic, empirically-oriented, tentative and curious way.
That is exactly the Cafe Sci view; science is a mindset not a method, or a mere body of facts; and there is no subject that it can't cover. There is no subject area that is, or is not, suitable for 'science'
The new Cornwall Science Community shares that view. For more background on the British Science Association itself, you can also check out the (national) website: HERE
Thursday, November 28, 2019
Special Event -
Big Data Challenges in Physics
We're very pleased to announce (in conjunction with Data Science Cornwall and the Institute for Physics), a special evening of talks by invited guests around the theme of big data in science.
Talk 1: Using Supercomputers to Search for the Breakdown of the Standard Model of Particle Physics
with Dr Craig McNeile,
Lecturer in Theoretical Physics, University of Plymouth.
Talk 2: The Challenge of Storing Ever Bigger Data
with Prof Robert J Hicken,
Professor of Condensed Matter Physics, University of Exeter
AIR (Academy of Research and Innovations),
Exeter University's Penryn campus
For full details of the talks and discussion programme (and to register), see:
Please note that you do not need to be an expert in data science or physics to enjoy the talks. They will have something for members at all levels to enjoy and take away.
2019 marks the 150th anniversary of the publication of Mendeleev's Periodic Table of the elements.
In this talk, we will explore the role of local science hero Humphrey Davy in the development of this work, a landmark in the development of the key project of modern physics - a unified theory of all matter.
We will also be describing the CSC's 'Patterns' competition for the creation of a new musical genre, a way to express the Periodic Table in the form of music; and the Crowdfunder appeal for help with the prizes.
January 15th, 7.30 for 7.45,
Falmouth Polytechnic, Library Room
The New Hadron Collider for Ideas.
January's Cafe Sci evening will be a re-run of the Hadron Collider - one of the innovations in the Cafe Sci format that we imported some years back from Nottingham Cafe Sci, where it was first developed.
For an introduction to the Hadron for Ideas, this video HERE explains and illustrates the basics with all due insouciance.
NB: Matt Creasey's talk is now postponed until still later in 2020
It's who you know...
With writer and researcher Mathew Creasey. Mathew's research focusses on individual differences in personality and cognition among individuals within cooperative groups.
Going with the flow
On the mixture of fluid dynamics and psychology in traffic management, with Andrew Archer, and Bert Biscoe, former policy holder for transport, Cornwall County Council.
Bert and Andrew will be discussing the science of flows, conflicts, urgencies and capacities.
Other topics in mind? Just let us know.......
We are always open to suggestions for topics....
For future Cornwall Science Community events across the whole of the Duchy, see the CSC website: https://cornwallsciencecommunity.org/
Later in 2020
Date to be confirmed (Postponed from November 21st, 2018 )
Should we be sharing health data?
With a panel of speakers - details t.b.c
NB: This talk on sharing health data is now postponed to the new year, as two of our intended speakers now find they are unable to manage this date
A national discussion, this year's series of Future Debates, hosted by/courtesy of the British Science Association in partnership with Genomics England. This round of Future Debates will consider the benefits and risks of a medical system that uses genomic data.
How should it be stored and who should have access? Should everyone's genome be analysed at birth? And is there a duty to donate your genome, like we do with blood and organs?
The British Science Association believes that science is a part of our everyday lives and that everyone should feel confident to talk about and be included in these topics. We want to empower everyone– not just scientists – to engage in conversation over science’s role in their own lives, their local economy, and the UK as a whole.
To make sure these conversations are happening at a local level, the BSA nationally is working with Genomics England to run this series of debates across the country, looking at specific topics relevant to today.
And for thse of you in Falmouth, we have another related discussion group in this remarkably busy little town -
The Philosopher's Hat
Described as 'a place in spacetime to discuss what really matters (or doesn't)', this is a discussion group aimed at providing people with a space and time to don their Philosopher’s Hat and chat about any topic they fancy, over a pint in the pub.
The group meets twice monthly on the 1st and 3rd Monday, at the Boathouse (pub), from 7pm.
More details from the website: HERE
and the Facebook page: HERE
Otherwise...... the National Maritime Museum have now launched a new website, which they intend to be far more accessible and interactive.
As they say:
" The brand new NMMC.CO.UK is part of an overall re-fresh of the museum’s digital brand which also includes social media, email and video.
"A new digital content strategy has increased the museum’s use of video content to communicate key messages and promote new events and exhibitions.... "
Check out their site, below.
Other local talks and events coming up:
Source Fm - Falmouth and Penryn's community radio - has a continuous programme of talks, music etc.
For their website and up-coming programme; see their website: HERE
At Redruth Cafe Sci
The Redruth Cafe is no longer meeting, for a while at least.
For details of past RCS talks, see their own website: HERE
Launceston Cafe Sci
See their website: HERE
At the Falmouth Polytechnic
The Poly is home to most of Falmouth Cafe Sci talks - and a lot else besides. The documentary talks programme is becoming fuller. For more details, see their own website: HERE
At the Maritime Museum
for details, see their own website: HERE
At Falmouth/Exeter Uni, Penryn campus
for details, see their website
NB: Throughout October of 2015 we ran, in conjunction with the Poly on Tuesday afternoons, an experimental MOOC-tracking discussion group.
What’s a MOOC, you ask (again)?
This link to a specific page on this site HERE will tell you all you need to know. But in short, think: internet book club: watch a video, or take a whole course of weekly reading - and come and discuss it with similarly enthused people.
With the advent of the Cornwall Science Community (see above), we might like to revive this idea. There is the possibility of making this a more regular feature of MOOC, CSC and Poly life, in 2020......
For future Cornwall Science Community events across the whole of the Duchy, see the CSC webite: https://cornwallsciencecommunity.org/
About Falmouth Cafe Scientifique
The Royal Cornwall Polytechnic Society ( a.k.a. "the Poly") is said to have been the first institution in this country to use the term "polytechnic" to describe the mixing of many skillsets in one educational endeavour.
Falmouth Cafe Scientifique: a pretty good pedigree
Falmouth Cafe Scientifique: a pretty good pedigree